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What evidence supports cyclical versus continuous Selank use?

Selank does not strictly need to be cycled for safety — it produces no dependence, tolerance, or withdrawal. However, standard protocols recommend 2–4 weeks on with 1–2 weeks off to maintain optimal sensitivity. The breaks allow receptor sensitivity to reset.

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  • Selank does not strictly need to be cycled for safety — it produces no dependence, tolerance, or withdrawal. However, standard protocols recommend 2–4 weeks on with 1–2 weeks off to maintain optimal sensitivity. The breaks allow receptor sensitivity to reset. Some practitioners use Selank continuously during high-stress periods and then take breaks when the acute need passes.
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