how to use sermorelin: Frequently asked questions

Sermorelin's effects are not immediately perceptible. Unlike exogenous GH, which produces acute changes in water retention and glucose metabolism within 48 hours, sermorelin amplifies endogenous GH pulses gradually. IGF-1 elevation takes 2–4 weeks to reach steady state, and measurable body composition changes require 8–12 weeks. Absence of subjective effects during week one is normal and expected. The only early indicators are improved sleep depth (reported by 40–60% of users within 10–14 days) and faster recovery from resistance training. If IGF-1 levels remain unchanged after 4 weeks, the peptide may be degraded or the dose insufficient.