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What is MOTS-c? MOTS-c is a 16 amino acid peptide that is coded by the mitochondrial genome. The mitochondria are the “power generators” in cells that convert chemical energy from food into a form that cells can use. Tw…
Read articleAbstract Mitochondrial ORF of the 12S rRNA Type-C (MOTS-c) is a mitochondrial-derived peptide composed of 16 amino acids encoded by the 12S rRNA region of the mitochondrial genome. The MOTS-c protein is transferred to t…
Read articleEvidence and status Approval status Not FDA approved Strongest support Human physiology and preclinical research Route context Reported practice; no established labeled route Competitive sport Prohibited in sport Lab wo…
Read articleFig. 1. Mitochondrial open reading frame of the 12S ribosomal RNA type-c (MOTS-c) prevents type 1 diabetes mellitus (T1DM). T1DM is an autoimmune disease. Activated autoreactive T-cells such as Th1 cells from secondary …
Read articleMOTS-c for metabolic disorders: Postmenopausal women often experience hormonal changes that can lead to metabolic dysfunction and an increased risk of conditions such as obesity and impaired insulin sensitivity. A study…
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