what temperature should tesamorelin be stored at: Frequently asked questions

Check the internal temperature with a fridge thermometer as soon as power returns. If the interior stayed below 10°C throughout the outage, the peptide is likely still viable. Refrigerators retain cold for 4–6 hours when unopened. If the temperature rose above 10°C for more than two hours, assume partial degradation. Lyophilised powder tolerates brief excursions better than reconstituted solution. Reconstituted vials exposed to 10–15°C for six hours lose 5–10% potency and should be used immediately or discarded. Extended outages (12+ hours) warrant replacement regardless of format.

Use a medical-grade cooling case that maintains 2–8°C for the duration of travel. FRIO wallets use evaporative cooling and work for 24–48 hours without electricity or ice. They're sufficient for domestic flights or road trips under two days. Longer trips require portable mini-fridges with battery packs or hotel refrigerator access. TSA allows medicated coolers and ice packs through security when declared as medical supplies. The vial must remain between 2–8°C continuously. A four-hour layover in a carry-on bag at cabin temperature (18–24°C) degrades potency measurably. Plan cold-chain logistics before departure, not at the airport.

Refrigerate it immediately and discontinue use. A reconstituted vial left at room temperature (20–25°C) for 8–12 hours has undergone significant hydrolytic and thermal degradation. HPLC assays show 15–20% potency loss within the first 12 hours, accelerating thereafter. Lyophilised powder exposed to the same conditions fares slightly better but still loses 5–10% potency. There is no home test to confirm remaining activity. The conservative approach is to discard the vial and reconstitute a fresh one. Using degraded peptide wastes injection effort and skews research data.

Discard it immediately. Properly reconstituted tesamorelin should be clear to slightly opalescent. Cloudiness indicates particulate formation from peptide aggregation or microbial contamination. Aggregation occurs when denatured peptides clump together, often triggered by temperature fluctuations or freeze-thaw cycles. Discolouration (yellowing, browning) signals oxidative degradation or bacterial growth. Bacteriostatic water prevents microbial proliferation under normal conditions, but compromised sterile technique during reconstitution or prolonged storage beyond 28 days increases contamination risk. Do not inject cloudy or discoloured solutions. The therapeutic effect is lost and injection-site reactions become likely.

Contact the supplier immediately and request a replacement. Gel packs are designed to maintain 2–8°C for 48–72 hours in transit. If the pack arrived fully melted and the peptide feels warm to the touch, the vial likely experienced prolonged temperature excursion. Most reputable suppliers like Real Peptides include temperature indicators or will replace shipments with documented cold-chain failure. Refrigerating a heat-exposed vial does not restore lost potency. Denaturation is irreversible. Using compromised peptide produces inconsistent results and unreliable data.