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Source comparison

10. Pulsatility preservation vs CJC-1295 with DAC

Tesamorelin’s ~30-40 minute half-life preserves physiological GH pulsatility when dosed once daily — the GH pulse occurs within the first 1-3 hours post-injection and returns to baseline. This is unlike CJC-1295 with DAC, which produces continuous GHRHR activa

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  • Tesamorelin’s ~30-40 minute half-life preserves physiological GH pulsatility when dosed once daily — the GH pulse occurs within the first 1-3 hours post-injection and returns to baseline. This is unlike CJC-1295 with DAC, which produces continuous GHRHR activation.
  • For research designs where pulsatility is important but longer action than sermorelin or CJC-1295 no-DAC is desired, tesamorelin occupies a useful intermediate pharmacokinetic niche.
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