Source comparison
Best Tesamorelin + Ipamorelin Blend Dosage: Protocol Comparison
Standard Blend (2026) 2mg 200mcg 30–60 min pre-sleep 18–24 Low (with 8-week cycles) Optimal ratio for maximizing GH pulse amplitude without cortisol elevation. Best supported by clinical kinetics data High-Dose Variant 3mg 300mcg 20–26 Moderate Marginally high
This comparison does not assign a generated winner or score.
- Standard Blend (2026)
- 2mg
- 200mcg
- 30–60 min pre-sleep
- 18–24
- Low (with 8-week cycles)
- Optimal ratio for maximizing GH pulse amplitude without cortisol elevation. Best supported by clinical kinetics data
- High-Dose Variant
- 3mg
- 300mcg
- 20–26
- Moderate
- Marginally higher GH peaks but 40% increase in cortisol and prolactin. Risk outweighs benefit for most research applications
- Low-Dose Introductory
- 1mg
- 100mcg
- 12–16
- Minimal
- Subtherapeutic for experienced users. Useful only for initial tolerance assessment in peptide-naive subjects
- Mistimed Protocol
- Immediately pre-sleep
- 12–14
- Low
- Timing error reduces GH response by 35–45%. Mechanistically sound doses wasted by poor synchronization with endogenous pulse
- Daytime Dosing
- Morning or midday
- 8–11
- Completely negates natural nocturnal GH pulse synergy. GH peaks are lower and cortisol interference is higher during waking hours