Source comparison
CJC-1295 & Ipamorelin Sleep Protocol: Method Comparison
Standard 1:1 Ratio 100mcg 45 min pre-bed Nightly (5–7 days/week) Increased slow-wave sleep duration, improved next-day recovery markers Most reliable starting point. Balanced GHRH and ghrelin pathway activation with minimal cortisol risk Conservative 2:1 Ratio
This comparison does not assign a generated winner or score.
- Standard 1:1 Ratio
- 100mcg
- 45 min pre-bed
- Nightly (5–7 days/week)
- Increased slow-wave sleep duration, improved next-day recovery markers
- Most reliable starting point. Balanced GHRH and ghrelin pathway activation with minimal cortisol risk
- Conservative 2:1 Ratio
- 50mcg
- Enhanced deep sleep consolidation, reduced sleep fragmentation
- Preferred for users sensitive to ghrelin or with baseline cortisol dysregulation
- Aggressive 1:1 High-Dose
- 150mcg
- 5 days/week (2-day break)
- Maximal GH pulse amplitude, significant recovery enhancement
- Risk of cortisol spillover above 250mcg total. Only for experienced users with confirmed cortisol baseline control
- Split-Dose (Non-Sleep Focus)
- 50mcg AM, 50mcg PM
- Upon waking + 45 min pre-bed
- Twice daily
- Elevated daytime GH, moderate sleep improvement
- Less effective for sleep-specific goals. Splits circadian alignment and reduces nocturnal pulse amplitude