Source comparison
CJC-1295 No DAC & Ipamorelin: Mechanism Comparison
CJC-1295 no DAC GHRH analog. Prolongs endogenous GH pulse duration GHRH receptor (Gs-protein coupled, cAMP cascade) ~30 minutes 2.1x baseline at 20–30 min None (selective GHRH agonism) Ipamorelin Ghrelin mimetic. Triggers GH release independent of GHRH Ghrelin
This comparison does not assign a generated winner or score.
- CJC-1295 no DAC
- GHRH analog. Prolongs endogenous GH pulse duration
- GHRH receptor (Gs-protein coupled, cAMP cascade)
- ~30 minutes
- 2.1x baseline at 20–30 min
- None (selective GHRH agonism)
- Ipamorelin
- Ghrelin mimetic. Triggers GH release independent of GHRH
- Ghrelin receptor (GHS-R1a, calcium mobilization)
- 2.8x baseline at 20–30 min
- Minimal cortisol/prolactin elevation (<5% vs GHRP-6)
- Combined Protocol
- Dual-pathway activation through separate signaling cascades
- GHRH + ghrelin receptors simultaneously
- ~30 minutes (both compounds)
- 8.3x baseline at 20–30 min
- Synergistic amplitude without receptor desensitization