Source comparison
CJC-1295 No DAC + Ipamorelin: Protocol Comparison
Single Evening Dose 100–200 mcg 200–300 mcg 30–60 min pre-sleep 2.8–4.2× baseline Captures largest nocturnal GH pulse. Simplest and most effective for most research applications Twice-Daily Split 100 mcg 150–200 mcg Morning (fasted) + evening pre-sleep 2.2–3.8
This comparison does not assign a generated winner or score.
- Single Evening Dose
- 100–200 mcg
- 200–300 mcg
- 30–60 min pre-sleep
- 2.8–4.2× baseline
- Captures largest nocturnal GH pulse. Simplest and most effective for most research applications
- Twice-Daily Split
- 100 mcg
- 150–200 mcg
- Morning (fasted) + evening pre-sleep
- 2.2–3.8× baseline per dose
- Targets both major pulse windows but requires early morning administration (4–6 AM). Impractical outside controlled settings
- Random Daytime Dosing
- Variable (no circadian alignment)
- 1.5–2.1× baseline
- Fights elevated somatostatin tone throughout the day. Significantly reduced efficacy compared to timed protocols
- CJC-1295 No DAC Alone
- 200 mcg
- N/A
- Evening pre-sleep
- 1.8–2.4× baseline
- Single-pathway GHRH stimulation. Misses ghrelin receptor synergy that doubles pulse amplitude
- Ipamorelin Alone
- 300 mcg
- 1.6–2.2× baseline
- Single-pathway ghrelin receptor stimulation. Misses GHRH-mediated cAMP amplification that sustains pulse duration