Source comparison
Comparison With Other GHRH Analogs: Half-Life Perspective
Sermorelin (1-29 NH2) ~2-3 min (rat) None Modified GRF 1-29 (CJC-1295 no DAC) ~30 min Amino acid substitutions CJC-1295 with DAC ~6-8 days Albumin binding via DAC Tesamorelin (1-40) ~30-40 min Extended C-terminus + modifications Native GHRH (1-44) ~2-3 min Non
This comparison does not assign a generated winner or score.
- Sermorelin (1-29 NH2)
- ~2-3 min (rat)
- None
- Modified GRF 1-29 (CJC-1295 no DAC)
- ~30 min
- Amino acid substitutions
- CJC-1295 with DAC
- ~6-8 days
- Albumin binding via DAC
- Tesamorelin (1-40)
- ~30-40 min
- Extended C-terminus + modifications
- Native GHRH (1-44)
- ~2-3 min
- None (also DPP-IV substrate)
- Table 3: Plasma half-life comparison across GHRH analogs in preclinical models.
- For Tesamorelin vs. Sermorelin comparison, see our dedicated comparison article.