Source comparison
Functional Medicine Practitioners BPC-157 Protocol: Comparison Table
Systemic gut-barrier repair 250–350mcg Abdominal subcutaneous Once daily 12–16 weeks Reduces intestinal permeability through tight junction protein upregulation Best for leaky gut, IBS, and autoimmune conditions driven by gut dysbiosis. Requires minimum 12 wee
This comparison does not assign a generated winner or score.
- Systemic gut-barrier repair
- 250–350mcg
- Abdominal subcutaneous
- Once daily
- 12–16 weeks
- Reduces intestinal permeability through tight junction protein upregulation
- Best for leaky gut, IBS, and autoimmune conditions driven by gut dysbiosis. Requires minimum 12 weeks to see mucosal healing
- Acute localized tendon injury
- 400–500mcg
- Peritendinous (within 2 inches of injury)
- Twice daily
- 4–8 weeks
- Drives angiogenesis and collagen deposition at injury site via VEGF and FGFR2 upregulation
- Most effective for acute injuries <6 weeks old. Chronic tendinopathies require longer cycles and adjunct physical therapy
- Chronic systemic inflammation
- 300–400mcg
- 8–12 weeks
- Modulates NF-κB signaling to reduce systemic cytokine load
- Functional medicine practitioners use this for chronic inflammatory conditions unresponsive to dietary intervention alone