Source comparison
Lyme Disease Researchers BPC-157 Protocol: Clinical vs Research Comparison
Animal Model Research 10 mcg/kg daily (SC) 2–4 weeks Tissue histology, cytokine levels, gut permeability markers None. Isolated intervention Demonstrates mechanism plausibility but cannot be directly translated to human dosing without allometric adjustment Cli
This comparison does not assign a generated winner or score.
- Animal Model Research
- 10 mcg/kg daily (SC)
- 2–4 weeks
- Tissue histology, cytokine levels, gut permeability markers
- None. Isolated intervention
- Demonstrates mechanism plausibility but cannot be directly translated to human dosing without allometric adjustment
- Clinical Case Reports
- 250–500 mcg daily (SC)
- 4–8 weeks
- Subjective symptom scores (fatigue, pain, cognition)
- Antimicrobials, probiotics, anti-inflammatory diet
- Most common protocol framework. Reflects real-world integrative practice but lacks placebo control
- Investigational Higher-Dose
- 750 mcg–1 mg daily (SC)
- 8–12 weeks
- Neurological symptom resolution, objective gut barrier testing (lactulose/mannitol)
- Standard Lyme treatment plus targeted microbiome support
- Reserved for severe PTLDS presentations. No safety data beyond case reports