Source comparison
Melanotan-1 Dosage Comparison by Skin Type and Objective
Type I–II (Very fair, burns easily) 0.25–0.5mg for 14 days 0.5mg 2–3×/week 10–14 days Nausea 20–30%, flushing common Start low. MC1R sensitivity highest in fair skin; aggressive dosing offers no timeline advantage Type III (Medium, tans gradually) 0.5–0.75mg f
This comparison does not assign a generated winner or score.
- Type I–II (Very fair, burns easily)
- 0.25–0.5mg for 14 days
- 0.5mg 2–3×/week
- 10–14 days
- Nausea 20–30%, flushing common
- Start low. MC1R sensitivity highest in fair skin; aggressive dosing offers no timeline advantage
- Type III (Medium, tans gradually)
- 0.5–0.75mg for 14 days
- 0.75mg 2×/week
- 7–10 days
- Nausea 10–15%, flushing mild
- Standard protocol. Most users tolerate 0.75mg well after day five
- Type IV–V (Olive to brown, tans easily)
- 0.75–1mg for 10–14 days
- 1mg 1–2×/week
- 5–8 days
- Nausea <10%, minimal flushing
- Higher baseline eumelanin means faster visible response; maintenance frequency lowest in this group
- Research/Photoprotection Focus
- 0.5–1mg daily for 21 days
- 0.5–1mg 3×/week
- N/A (objective is melanin density, not cosmetic darkening)
- Varies with dose
- Clinical photoprotection trials used sustained-release implants equivalent to ~0.27mg/day; subcutaneous protocols at 0.5–1mg produce higher peak melanin levels