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Source comparison

Melanotan-2 Dosing: Loading vs Maintenance Comparison

Loading Phase 0.25–0.5mg Daily 5–7 days Start day 4, 4–6 hours post-injection, 10–15 min Receptor saturation, initial melanogenesis, baseline tan established Maintenance Phase 0.5–1mg Twice weekly (e.g., Mon/Thu) Ongoing (8–12 weeks typical) Same day as inject

This comparison does not assign a generated winner or score.

  • Loading Phase
  • 0.25–0.5mg
  • Daily
  • 5–7 days
  • Start day 4, 4–6 hours post-injection, 10–15 min
  • Receptor saturation, initial melanogenesis, baseline tan established
  • Maintenance Phase
  • 0.5–1mg
  • Twice weekly (e.g., Mon/Thu)
  • Ongoing (8–12 weeks typical)
  • Same day as injection, 4–6 hours after, 15–20 min
  • Sustained pigmentation, minimal fading between doses
  • Off-Cycle (Post-Protocol)
  • None
  • N/A
  • 4–8 weeks minimum
  • Optional. Tan fades 30–50% over 6 weeks
  • Gradual melanin degradation, return to baseline skin tone
  • Professional Assessment
  • Loading establishes the tan; maintenance preserves it. Skipping UV during loading wastes the peptide. Exceeding 1mg per injection increases nausea risk without additional tanning benefit.
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