Melanotan-2 Dosing: Loading vs Maintenance Comparison
Loading Phase 0.25–0.5mg Daily 5–7 days Start day 4, 4–6 hours post-injection, 10–15 min Receptor saturation, initial melanogenesis, baseline tan established Maintenance Phase 0.5–1mg Twice weekly (e.g., Mon/Thu) Ongoing (8–12 weeks typical) Same day as inject
This comparison does not assign a generated winner or score.
- Loading Phase
- 0.25–0.5mg
- Daily
- 5–7 days
- Start day 4, 4–6 hours post-injection, 10–15 min
- Receptor saturation, initial melanogenesis, baseline tan established
- Maintenance Phase
- 0.5–1mg
- Twice weekly (e.g., Mon/Thu)
- Ongoing (8–12 weeks typical)
- Same day as injection, 4–6 hours after, 15–20 min
- Sustained pigmentation, minimal fading between doses
- Off-Cycle (Post-Protocol)
- None
- N/A
- 4–8 weeks minimum
- Optional. Tan fades 30–50% over 6 weeks
- Gradual melanin degradation, return to baseline skin tone
- Professional Assessment
- Loading establishes the tan; maintenance preserves it. Skipping UV during loading wastes the peptide. Exceeding 1mg per injection increases nausea risk without additional tanning benefit.