Source comparison
Peptides for Strength Athletes Powerlifting CrossFit — Comparison
MK-677 (Ibutamoren) Ghrelin receptor agonist. Increases GH and IGF-1 systemically 12.5–25mg orally once daily, preferably before bed Sustained IGF-1 elevation supports protein synthesis and connective tissue repair across high-frequency training blocks Can cau
This comparison does not assign a generated winner or score.
- MK-677 (Ibutamoren)
- Ghrelin receptor agonist. Increases GH and IGF-1 systemically
- 12.5–25mg orally once daily, preferably before bed
- Sustained IGF-1 elevation supports protein synthesis and connective tissue repair across high-frequency training blocks
- Can cause insulin resistance and water retention at higher doses; requires 2–4 weeks to reach steady-state IGF-1 levels
- CJC-1295 + Ipamorelin
- GHRH analog + selective ghrelin agonist. Pulsatile GH release
- 100–200mcg each, injected subcutaneously 3–5× weekly
- Mimics natural GH rhythm without chronic elevation; supports recovery between sessions and lipolysis during fat loss phases
- Requires subcutaneous injection; effects diminish if dosed too frequently (daily use reduces receptor sensitivity)
- BPC-157
- Synthetic gastric peptide. Promotes angiogenesis and fibroblast proliferation in damaged tissue
- 250–500mcg daily, injected near injury site for 4–6 weeks
- Accelerates tendon and ligament healing; reduces recovery time from overuse injuries common in powerlifting and CrossFit
- Evidence is primarily from animal models; human clinical trials are limited; does not replace proper load management
- TB-500 (Thymosin Beta-4)
- Actin-binding peptide. Increases cell migration and reduces fibrosis during tissue remodeling
- 2–5mg subcutaneously 2× weekly for 4–6 weeks, then 1× weekly maintenance
- Reduces scar tissue formation during injury recovery; supports flexibility and range of motion in healing tendons
- Long half-life means effects take weeks to manifest; expensive relative to other peptides; not a short-term solution