Source comparison
Sermorelin Dosage Protocol Guide: Clinical Comparison Table
Conservative (High Receptor Density) 200 mcg nightly +100 mcg weekly for 3–4 weeks 300–500 mcg 50–70 ng/mL above baseline Best for older adults or those with prior GH therapy. Minimises desensitisation risk Standard Research Protocol +150 mcg weekly for 4 week
This comparison does not assign a generated winner or score.
- Conservative (High Receptor Density)
- 200 mcg nightly
- +100 mcg weekly for 3–4 weeks
- 300–500 mcg
- 50–70 ng/mL above baseline
- Best for older adults or those with prior GH therapy. Minimises desensitisation risk
- Standard Research Protocol
- +150 mcg weekly for 4 weeks
- 500–700 mcg
- 70–100 ng/mL above baseline
- Most common clinical approach. Balances efficacy and receptor preservation
- Aggressive (Low Receptor Density)
- 250 mcg nightly
- +200 mcg weekly for 4–5 weeks
- 700–1000 mcg
- 80–120 ng/mL above baseline
- Reserved for subjects with confirmed low baseline IGF-1 and poor initial response
- Maintenance Post-Titration
- Individualised (300–1000 mcg)
- No further escalation
- Same as titration endpoint
- Sustain 60–100 ng/mL elevation
- Dose remains fixed once IGF-1 plateau is reached. Further increases add no benefit