Source comparison
Sermorelin for Men 35-45: Type Comparison
Sermorelin (GHRH analog) Stimulates endogenous GH release via pituitary GHRH receptors 11-12 minutes Nightly before sleep 200-500 mcg subcutaneous Preserves natural pulsatile GH dynamics; minimal feedback disruption; short half-life requires daily dosing GHRP-
This comparison does not assign a generated winner or score.
- Sermorelin (GHRH analog)
- Stimulates endogenous GH release via pituitary GHRH receptors
- 11-12 minutes
- Nightly before sleep
- 200-500 mcg subcutaneous
- Preserves natural pulsatile GH dynamics; minimal feedback disruption; short half-life requires daily dosing
- GHRP-2 (GH secretagogue)
- Stimulates GH release via ghrelin receptors; synergistic with GHRH analogs
- ~30 minutes
- 1-3x daily
- 100-300 mcg per dose
- Higher GH amplitude than sermorelin alone; often stacked with GHRH analogs for additive effect
- MK-677 (oral GH secretagogue)
- Oral ghrelin receptor agonist; mimics ghrelin signaling
- 4-6 hours (oral)
- Once daily
- 12.5-25 mg oral
- Convenient oral administration; longer half-life risks desensitisation; elevates appetite significantly
- CJC-1295 (modified GHRH)
- Extended GHRH analog with drug affinity complex (DAC)
- 6-8 days
- 1-2x weekly
- 1-2 mg per injection
- Sustained GH elevation over days; less physiological pulsatility; fewer injections required