Source comparison
Sermorelin vs CJC-1295, Ipamorelin, Tesamorelin, and Direct GH
Choosing the right GH-enhancing compound depends on your goals, budget, and risk tolerance. Each option has a distinct mechanism, half-life, and evidence base for fat loss. Sermorelin (GRF 1-29) GHRH receptor agonist 10-20 min Clinical trials in GH-deficient a
This comparison does not assign a generated winner or score.
- Choosing the right GH-enhancing compound depends on your goals, budget, and risk tolerance. Each option has a distinct mechanism, half-life, and evidence base for fat loss.
- Sermorelin (GRF 1-29)
- GHRH receptor agonist
- 10-20 min
- Clinical trials in GH-deficient adults
- $$
- CJC-1295 (with DAC)
- Modified GHRH analog
- 6-8 days
- Sustained GH/IGF-1 elevation; limited fat-specific trials
- Ipamorelin
- Ghrelin receptor agonist (GHRP)
- 2 hours
- GH pulse amplification; body composition studies
- Tesamorelin
- GHRH analog (44 AA)
- 26-38 min
- FDA-approved for HIV lipodystrophy; strong visceral fat data
- $$$
- Exogenous GH (HGH)
- Direct GH replacement
- 3-5 hours
- Extensive; 10-20% body fat reduction in GH-deficient adults
- $$$$