Sermorelin vs CJC-1295 vs Ipamorelin: Complete Comparison
The table below summarizes the sermorelin vs CJC-1295 vs ipamorelin comparison at a glance. Peptide Class GHRH analogue Modified GHRH analogue Modified GHRH + albumin binding Growth hormone secretagogue Receptor Target GHRH-R GHS-R1a (ghrelin receptor) Half-Li
This comparison does not assign a generated winner or score.
- The table below summarizes the sermorelin vs CJC-1295 vs ipamorelin comparison at a glance.
- Peptide Class
- GHRH analogue
- Modified GHRH analogue
- Modified GHRH + albumin binding
- Growth hormone secretagogue
- Receptor Target
- GHRH-R
- GHS-R1a (ghrelin receptor)
- Half-Life
- 10-20 min
- ~30 min
- 6-8 days
- ~2 hours
- GH Release Pattern
- Acute pulse, physiological
- Acute pulse, slightly extended
- Sustained elevation (blunts pulsatility)
- Cortisol Effect
- Minimal increase
- No significant increase
- Prolactin Effect
- None
- Appetite Effect
- Minimal (unlike GHRP-6)
- Clinical Data
- FDA-approved (pediatric GHD, withdrawn)
- Limited human PK data
- Phase 2 data
- Typical Administration
- 1x daily (evening)
- 1-3x daily
- 1-2x weekly