Source comparison
Side-by-Side Structural Comparison
Amino acid length 70 aa 83 aa Molecular weight ~7.6 kDa ~9.1 kDa N-terminal extension None 13-aa extension Position 3 residue Glutamic acid (Glu) Arginine (Arg) IGFBP affinity High ~1,000x reduced Receptor binding affinity (IGF-1R) Comparable to native Approxi
This comparison does not assign a generated winner or score.
- Amino acid length
- 70 aa
- 83 aa
- Molecular weight
- ~7.6 kDa
- ~9.1 kDa
- N-terminal extension
- None
- 13-aa extension
- Position 3 residue
- Glutamic acid (Glu)
- Arginine (Arg)
- IGFBP affinity
- High
- ~1,000x reduced
- Receptor binding affinity (IGF-1R)
- Comparable to native
- Approximate half-life
- 10–20 min (free form)
- ~20–30 hours
- Primary use in research
- In vitro signaling studies
- Extended preclinical in vivo models