Melanotan-2 PT-141 Protocol Research: Structural Comparison
Chemical Structure Linear heptapeptide (Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2) Cyclic heptapeptide (Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2 with lactam bridge) Cyclisation reduces MC1R affinity by ~7…