Source comparison
Best Kisspeptin Dosage for GnRH Stimulation: Research Comparison
Physiological pulsatile stimulation 0.24–1.0 nmol/kg 0.75–3.0 nmol/kg 2–5 IU/L peak, mirrors endogenous pulse 60–90 min intervals, 24–48 hr Hypothalamic amenorrhea models, pubertal timing research Maximal GnRH neuron activation 1.0–4.0 nmol/kg 3.0–12.0 nmol/kg
This comparison does not assign a generated winner or score.
- Physiological pulsatile stimulation
- 0.24–1.0 nmol/kg
- 0.75–3.0 nmol/kg
- 2–5 IU/L peak, mirrors endogenous pulse
- 60–90 min intervals, 24–48 hr
- Hypothalamic amenorrhea models, pubertal timing research
- Maximal GnRH neuron activation
- 1.0–4.0 nmol/kg
- 3.0–12.0 nmol/kg
- 8–15 IU/L peak, plateau above 4.0 nmol/kg
- Single bolus or 2-dose protocol
- Pituitary reserve testing, PCOS mechanistic studies
- Receptor sensitivity mapping
- 0.01–0.1 nmol/kg
- 0.03–0.3 nmol/kg
- 0.5–2.0 IU/L, threshold detection
- Single dose with serial sampling
- GPR54 variant characterisation, metabolic hypogonadism
- Continuous infusion desensitisation
- 4.0 nmol/kg/hr continuous
- Not applicable
- LH suppression after 6–12 hr
- 24–72 hr infusion
- GnRH receptor downregulation models