Source comparison
Best Kisspeptin Dosage for Testosterone: Protocol Comparison
| Protocol Type | Dose (nmol/kg) | Route | Timing | LH Response (Fold Increase) | Testosterone Peak (% Increase) | Professional Assessment ||—|—|—|—|—|—|| Single IV Bolus | 1–2 | IV | Once | 3–5× baseline at 60 min | 200–300% at 120–180 min | Effective for acu
This comparison does not assign a generated winner or score.
- | Protocol Type | Dose (nmol/kg) | Route | Timing | LH Response (Fold Increase) | Testosterone Peak (% Increase) | Professional Assessment ||—|—|—|—|—|—|| Single IV Bolus | 1–2 | IV | Once | 3–5× baseline at 60 min | 200–300% at 120–180 min | Effective for acute HPG activation in single-session research; not sustainable beyond 3–4 hours due to peptide clearance || Pulsatile IV (90-min intervals) | 1.5 per pulse | IV | Every 90 min × 14 days | Sustained 4–6× baseline | Sustained 250–350% elevation | Gold standard for prolonged HPG stimulation; mimics physiological GnRH pulsatility without receptor desensitization || Continuous IV Infusion | 1–2/hour | IV | 24-hour infusion | 3× at 12 hours, <1.5× at 48 hours | Peaks at 24 hours, suppressed by 72 hours | Useful for first 24–48 hours only; receptor internalization makes this approach unsustainable for multi-day protocols || Subcutaneous Bolus | 5–10 | SC | Once | 2–3× baseline at 120 min | 150–200% at 180–240 min | Lower bioavailability r