Source comparison
Best Melanotan-2 Dosage for Erectile Function: Type Comparison
Loading Phase + Maintenance 0.25–0.5mg daily for 5–7 days, then 1–1.5mg as needed Daily loading, then 2–3×/week 15–25% during loading, <10% at maintenance 90–180 minutes post-injection Lowest side effect profile with predictable threshold identification. Best
This comparison does not assign a generated winner or score.
- Loading Phase + Maintenance
- 0.25–0.5mg daily for 5–7 days, then 1–1.5mg as needed
- Daily loading, then 2–3×/week
- 15–25% during loading, <10% at maintenance
- 90–180 minutes post-injection
- Lowest side effect profile with predictable threshold identification. Best for first-time users
- Single High-Dose (No Loading)
- 1.5–2mg per administration
- As needed, 1–3 hours pre-activity
- 50–60% on first dose, decreases with repeated use
- 60–120 minutes post-injection
- Faster protocol but higher initial nausea risk. Suitable for users with known tolerance
- Low-Dose Intermittent
- 0.5–0.75mg per administration
- 2–3×/week, no daily loading
- 10–15% overall
- 120–180 minutes post-injection
- Minimal side effects but may require higher cumulative dose over time to maintain effects
- Daily Maintenance (Chronic)
- 1–1.5mg daily
- Daily for extended periods
- Initial 20–30%, stabilises to <15%
- 90–150 minutes post-injection
- Risk of receptor downregulation and tolerance after 4–6 weeks. Not recommended for long-term sexual health protocols
- The loading phase protocol consistently demonstrates the best balance between efficacy and tolerability across diverse user populations. Single high-dose approaches work for individuals prioritising speed over side effect management, but discontinuation rates are significantly higher in this group.