Source comparison
Best Melanotan-2 Dosage for Skin Pigmentation: Dosing Protocol Comparison
Loading Phase 0.25mg Daily for 5–7 days 2–4 hours post-injection MC1R priming, minimal pigmentation, reduced nausea risk Start here. Receptor saturation without off-target effects Escalation Phase 0.5–1.0mg Daily for 10–21 days Progressive pigmentation, visibl
This comparison does not assign a generated winner or score.
- Loading Phase
- 0.25mg
- Daily for 5–7 days
- 2–4 hours post-injection
- MC1R priming, minimal pigmentation, reduced nausea risk
- Start here. Receptor saturation without off-target effects
- Escalation Phase
- 0.5–1.0mg
- Daily for 10–21 days
- Progressive pigmentation, visible tan by day 14
- Dose ceiling. Above 1.0mg doesn't increase pigmentation
- Maintenance Phase
- 2–3 times weekly
- Sustained pigmentation without receptor downregulation
- Maintenance prevents tan fade; daily dosing unnecessary
- High-Dose (Not Recommended)
- >1.5mg
- Daily
- Variable
- Elevated nausea, flushing, no additional pigmentation
- Exceeds MC1R binding capacity. Adverse events rise 340%