Source comparison
Best NAD+ Dosage Cognitive Function 2026: Delivery Method Comparison
Subcutaneous Injection 250–500mg per session, 2–3×/week 85–90% 30–45 minutes 8–12 weeks at 250mg twice weekly Highest efficiency, requires injection skill, best for acute decline Sublingual NMN/NR 500–750mg daily 40–50% 60–90 minutes 8–12 weeks at 500mg daily
This comparison does not assign a generated winner or score.
- Subcutaneous Injection
- 250–500mg per session, 2–3×/week
- 85–90%
- 30–45 minutes
- 8–12 weeks at 250mg twice weekly
- Highest efficiency, requires injection skill, best for acute decline
- Sublingual NMN/NR
- 500–750mg daily
- 40–50%
- 60–90 minutes
- 8–12 weeks at 500mg daily
- Balanced convenience and absorption, ideal for age 40+ maintenance
- Oral Capsule NMN/NR
- 750–1000mg daily
- 10–15%
- 120–180 minutes
- 12–16 weeks at 750mg daily
- Lowest efficiency, highest dose required, GI tolerance limiting factor
- IV Infusion NAD+
- 250–500mg per session, weekly
- ~95%
- Immediate
- 4–8 weeks at 500mg weekly
- Maximum bioavailability, clinical setting required, cost-prohibitive for maintenance