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Best Peptides for Growth Hormone Deficiency Adults: Comparison

Hexarelin Ghrelin mimetic + CD36 agonist 10-13× baseline 70 minutes 24-36 hours Moderate (some prolactin/cortisol) Highest acute GH response, cardiac research models CJC-1295 (with DAC) GHRH analog with albumin binding 3-5× baseline 6-8 days 9-11 days High (GH

This comparison does not assign a generated winner or score.

  • Hexarelin
  • Ghrelin mimetic + CD36 agonist
  • 10-13× baseline
  • 70 minutes
  • 24-36 hours
  • Moderate (some prolactin/cortisol)
  • Highest acute GH response, cardiac research models
  • CJC-1295 (with DAC)
  • GHRH analog with albumin binding
  • 3-5× baseline
  • 6-8 days
  • 9-11 days
  • High (GHRH receptor only)
  • Long-duration IGF-1 elevation, minimal dosing frequency
  • Ipamorelin
  • Selective ghrelin mimetic
  • 4-6× baseline
  • 2 hours
  • 8-12 hours
  • Very high (no cortisol/prolactin)
  • Safest ghrelin analog for long-term protocols
  • MK-677 (Ibutamoren)
  • Oral ghrelin mimetic
  • 2-4× baseline (sustained)
  • 24 hours
  • Continuous with daily dosing
  • Moderate (increases appetite, glucose)
  • Once-daily oral dosing, research in sarcopenia
  • MOD-GRF (1-29)
  • Short-acting GHRH analog
  • 3-4× baseline
  • 30 minutes
  • 4-6 hours
  • Timed dosing around sleep/exercise windows
  • GHRP-6
  • Non-selective ghrelin mimetic
  • 6-8× baseline
  • 20 minutes
  • 6-8 hours
  • Low (stimulates appetite, cortisol, prolactin)
  • Appetite stimulation research, less used in GHD
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