Best Peptides for Growth Hormone Deficiency Adults: Comparison
Hexarelin Ghrelin mimetic + CD36 agonist 10-13× baseline 70 minutes 24-36 hours Moderate (some prolactin/cortisol) Highest acute GH response, cardiac research models CJC-1295 (with DAC) GHRH analog with albumin binding 3-5× baseline 6-8 days 9-11 days High (GH
This comparison does not assign a generated winner or score.
- Hexarelin
- Ghrelin mimetic + CD36 agonist
- 10-13× baseline
- 70 minutes
- 24-36 hours
- Moderate (some prolactin/cortisol)
- Highest acute GH response, cardiac research models
- CJC-1295 (with DAC)
- GHRH analog with albumin binding
- 3-5× baseline
- 6-8 days
- 9-11 days
- High (GHRH receptor only)
- Long-duration IGF-1 elevation, minimal dosing frequency
- Ipamorelin
- Selective ghrelin mimetic
- 4-6× baseline
- 2 hours
- 8-12 hours
- Very high (no cortisol/prolactin)
- Safest ghrelin analog for long-term protocols
- MK-677 (Ibutamoren)
- Oral ghrelin mimetic
- 2-4× baseline (sustained)
- 24 hours
- Continuous with daily dosing
- Moderate (increases appetite, glucose)
- Once-daily oral dosing, research in sarcopenia
- MOD-GRF (1-29)
- Short-acting GHRH analog
- 3-4× baseline
- 30 minutes
- 4-6 hours
- Timed dosing around sleep/exercise windows
- GHRP-6
- Non-selective ghrelin mimetic
- 6-8× baseline
- 20 minutes
- 6-8 hours
- Low (stimulates appetite, cortisol, prolactin)
- Appetite stimulation research, less used in GHD