Source comparison
Best Peptides for Growth Hormone: Research Protocol Comparison
CJC-1295 (no DAC) Moderate (6–10 ng/mL) 30 minutes Low 12–16 weeks continuous Best for replicating endogenous pulsatility without long-term suppression. Ideal when circadian GH dynamics must remain intact CJC-1295 (with DAC) Low sustained (3–5 ng/mL baseline e
This comparison does not assign a generated winner or score.
- CJC-1295 (no DAC)
- Moderate (6–10 ng/mL)
- 30 minutes
- Low
- 12–16 weeks continuous
- Best for replicating endogenous pulsatility without long-term suppression. Ideal when circadian GH dynamics must remain intact
- CJC-1295 (with DAC)
- Low sustained (3–5 ng/mL baseline elevation)
- 6–8 days
- None (suppresses endogenous pulses)
- 8–12 weeks with 4-week washout
- Mimics exogenous GH replacement. Use when sustained elevation matters more than pulsatility
- Ipamorelin
- Moderate-high (8–12 ng/mL)
- 2 hours
- Minimal
- 16+ weeks continuous
- Closest analog to natural GH secretion with negligible cortisol/prolactin co-release. Gold standard for long-term protocols
- Hexarelin
- Very high (15–25 ng/mL)
- 70 minutes
- Severe (60% reduction by week 2)
- 2–4 weeks on, 4–6 weeks off
- Highest acute GH response but rapid receptor desensitization. Reserve for short-term mechanistic studies
- GHRP-2
- Moderate (4–8 ng/mL)
- 20 minutes
- Low-moderate
- 8–12 weeks continuous
- Balanced GH stimulation with ghrelin-mediated appetite increase. Useful in metabolic research but complicates calorie-controlled models
- MK-677 (ibutamoren)
- Moderate sustained (4–6 ng/mL)
- 24 hours (oral bioavailability)
- Moderate (appetite increase)
- Oral administration simplifies protocols but sustained ghrelin agonism elevates appetite and insulin. Not a pure GH analog