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Melanotan-2 Dosage Comparison: Loading vs Maintenance Protocols

Loading (Type I–II) 0.25–0.5mg daily 10–14 days Visible tan by day 7–10; moderate depth by day 14 Nausea 15–25%, flushing 10–20%, minimal sexual sides at low dose Best for fair skin. Slow ramp minimises uneven pigmentation and mole darkening Loading (Type III–

This comparison does not assign a generated winner or score.

  • Loading (Type I–II)
  • 0.25–0.5mg daily
  • 10–14 days
  • Visible tan by day 7–10; moderate depth by day 14
  • Nausea 15–25%, flushing 10–20%, minimal sexual sides at low dose
  • Best for fair skin. Slow ramp minimises uneven pigmentation and mole darkening
  • Loading (Type III–IV)
  • 0.5–0.75mg daily
  • 7–10 days
  • Visible tan by day 5–7; deep tan by day 10
  • Nausea 25–35%, flushing 20–30%, spontaneous erections 10–15%
  • Standard protocol for medium skin. Faster results with manageable sides
  • Aggressive Loading
  • 1mg daily
  • 5–7 days
  • Rapid pigmentation within 5 days
  • Nausea 40–50%, flushing 35–45%, sexual sides 20–30%
  • High side effect burden without proportional benefit. Receptor saturation limits gains
  • Maintenance (All Types)
  • 0.25–0.5mg 2–3x weekly
  • Indefinite
  • Sustains existing pigmentation without further darkening
  • Nausea <10%, flushing <10%, minimal sides at low frequency
  • Optimal for sustaining tan. Matches melanin turnover rate without overshooting
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