Source comparison
Melanotan-2 Dosing: Protocol Comparison
Conservative (evidence-based) 0.25mg daily × 5–7 days, then 0.5mg daily 10–14 days 15–20% 0.5mg 2×/week Prioritises tolerability; slower onset but higher compliance Moderate (hybrid) 0.5mg daily from day 1 7–10 days 35–45% 0.75mg 2×/week Balances speed and sid
This comparison does not assign a generated winner or score.
- Conservative (evidence-based)
- 0.25mg daily × 5–7 days, then 0.5mg daily
- 10–14 days
- 15–20%
- 0.5mg 2×/week
- Prioritises tolerability; slower onset but higher compliance
- Moderate (hybrid)
- 0.5mg daily from day 1
- 7–10 days
- 35–45%
- 0.75mg 2×/week
- Balances speed and side effects; common in informed user communities
- Aggressive (forum standard)
- 1mg daily loading phase
- 5–7 days
- 60–75%
- 1mg 2×/week
- Fastest pigmentation but highest discontinuation rate due to nausea
- Microdosing (experimental)
- 0.1–0.15mg daily continuous
- 18–24 days
- <5%
- Same dose daily indefinitely
- Minimal nausea; very gradual tan; not yet clinically validated
- Professional Assessment
- The 0.25mg → 0.5mg protocol delivers equivalent final pigmentation to aggressive dosing with 70% fewer reported adverse events. Speed difference is 3–5 days, tolerability difference is substantial.