Source comparison
TB-500 Research Progress Markers: Tissue Healing vs Angiogenesis Comparison
Fibroblast migration distance Immunofluorescence (α-SMA staining) Days 7–21 1.5–2.0× increase from wound edge Migration plateaus by day 10 Faster wound closure, reduced scarring Capillary density CD31 immunostaining (vessels/mm²) Days 10–21 2.0–2.5× increase v
This comparison does not assign a generated winner or score.
- Fibroblast migration distance
- Immunofluorescence (α-SMA staining)
- Days 7–21
- 1.5–2.0× increase from wound edge
- Migration plateaus by day 10
- Faster wound closure, reduced scarring
- Capillary density
- CD31 immunostaining (vessels/mm²)
- Days 10–21
- 2.0–2.5× increase vs baseline
- Minimal neovascularisation
- Improved oxygen and nutrient delivery to healing tissue
- Collagen deposition
- Masson's trichrome staining
- Weeks 2–4
- 1.8–2.3× organised collagen density
- Disorganised fibrous tissue
- Structural integrity restoration
- Serum IL-6 (pg/mL)
- ELISA cytokine panel
- Days 3–10
- 40–60% reduction from acute peak
- Sustained elevation
- Reduced chronic inflammation without immune suppression
- Tensile strength
- Biomechanical load testing (Newtons)
- Week 4+
- 30–45% greater force-to-failure
- Weakened tissue integrity
- Functional recovery. Tissue can withstand physiological loads