Tesamorelin is a synthetic GHRH analog that stimulates endogenous growth hormone production. It is the only FDA-approved treatment for reducing visceral fat in HIV-associated lipodystrophy, with Phase III trial data sho…
Read articleTesamorelin is one of the few peptides with FDA approval and Phase III clinical trial data behind it. Originally approved for HIV-associated lipodystrophy, its benefits extend well beyond that population — spanning visc…
Read articleThe Cancer-Concern Context TB-4's pro-angiogenic and pro-migratory mechanism — the same property that enables wound healing — has prompted theoretical concern in users with active malignancy or strong personal cancer hi…
Read articleTB-500 is a synthetic 17-amino-acid fragment of Thymosin Beta-4, containing the active actin-binding domain responsible for cell migration and tissue repair. It's a cornerstone of healing peptide protocols, especially w…
Read articleTB-500 is a synthetic fragment of thymosin beta-4, a 43-amino-acid peptide that the body releases naturally after injury. It contains the active region (the Ac-SDKP actin-binding domain) responsible for cell migration, …
Read articleAffiliate disclosure: vendor links in this article are affiliate links — The Peptide Catalog may earn a commission if you buy through them, at no additional cost to you. Where These Numbers Come From Community doses are…
Read articleOn April 12, 2026, the journal Sports Medicine published a peer-reviewed review by Christopher L. Mendias and colleagues titled "Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injur…
Read articleThe "exercise mimetic" label gets stuck on multiple compounds, but they are not interchangeable. SLU-PP-332 and MOTS-c both produce a transcriptional and metabolic phenotype that overlaps with what endurance training pr…
Read articleSelf-Reported Community Adverse Events for Adult Use Note on labeling: the events below come from r/peptides, r/PeptideTherapy, and community forums for adult subcutaneous sermorelin use, typically at doses substantiall…
Read articleSermorelin is a synthetic version of the first 29 amino acids of human growth hormone-releasing hormone (GHRH). It was formerly FDA-approved for GH deficiency diagnosis, giving it a unique history of clinical safety dat…
Read articleSermorelin is a synthetic analog of growth hormone-releasing hormone (GHRH) — specifically the first 29 amino acids of the 44-amino-acid native hormone. It binds the GHRH receptor on pituitary somatotrophs, triggering n…
Read articleSelf-Reported Community Adverse Events Note on labeling: the events below come from r/nootropics, r/peptides, and community forums for intranasal research-peptide semax use, typically at lower doses than Russian stroke …
Read articleAffiliate disclosure: vendor links in this article are affiliate links — The Peptide Catalog may earn a commission if you buy through them, at no additional cost to you. Reconstitution Quick Reference 30 mg 3 mL 10 mg/m…
Read articleSelank is a synthetic heptapeptide derived from the endogenous immunomodulatory peptide tuftsin, developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. It is approved in Russia as a nasal s…
Read articleBP and Cardiovascular Considerations The Phase 3 program documented modest, transient increases in systolic blood pressure (1.9-2.5 mmHg) and diastolic (1.7-1.8 mmHg) in the 4-6 hours after dosing. Heart rate increased …
Read articlePT-141 (bremelanotide) is a cyclic melanocortin receptor agonist that enhances sexual desire and arousal through a mechanism no other approved sexual health treatment uses: direct activation of MC4R receptors in the bra…
Read articleIV Infusion Self-Reported Adverse Events Note on labeling: the events below come from clinic-published infusion procedures and self-reported community sources. There is no Phase 2 or Phase 3 trial dataset for IV NAD+ ad…
Read articleNAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every living cell, essential for mitochondrial energy production, DNA repair, and sirtuin activation. NAD+ levels decline approximately 50% between ages …
Read articleNicotinamide adenine dinucleotide (NAD+) is not a peptide — it's a coenzyme found in every living cell. But its role in aging biology is so central that it's become one of the most researched molecules in the longevity …
Read articleWhy MOTS-c and Metformin Get Compared Both MOTS-c and metformin activate AMP-activated protein kinase (AMPK) — the cellular energy sensor that sits at the crossroads of metabolism, aging, and exercise adaptation. That s…
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