TB-500 is a synthetic fragment of thymosin beta-4, a 43-amino-acid peptide that the body releases naturally after injury. It contains the active region (the Ac-SDKP actin-binding domain) responsible for cell migration, …
Affiliate disclosure: vendor links in this article are affiliate links — The Peptide Catalog may earn a commission if you buy through them, at no additional cost to you. Where These Numbers Come From Community doses are…
On April 12, 2026, the journal Sports Medicine published a peer-reviewed review by Christopher L. Mendias and colleagues titled "Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injur…
The "exercise mimetic" label gets stuck on multiple compounds, but they are not interchangeable. SLU-PP-332 and MOTS-c both produce a transcriptional and metabolic phenotype that overlaps with what endurance training pr…
Self-Reported Community Adverse Events for Adult Use Note on labeling: the events below come from r/peptides, r/PeptideTherapy, and community forums for adult subcutaneous sermorelin use, typically at doses substantiall…
Sermorelin is a synthetic version of the first 29 amino acids of human growth hormone-releasing hormone (GHRH). It was formerly FDA-approved for GH deficiency diagnosis, giving it a unique history of clinical safety dat…
Sermorelin is a synthetic analog of growth hormone-releasing hormone (GHRH) — specifically the first 29 amino acids of the 44-amino-acid native hormone. It binds the GHRH receptor on pituitary somatotrophs, triggering n…
Self-Reported Community Adverse Events Note on labeling: the events below come from r/nootropics, r/peptides, and community forums for intranasal research-peptide semax use, typically at lower doses than Russian stroke …
Affiliate disclosure: vendor links in this article are affiliate links — The Peptide Catalog may earn a commission if you buy through them, at no additional cost to you. Reconstitution Quick Reference 30 mg 3 mL 10 mg/m…
Selank is a synthetic heptapeptide derived from the endogenous immunomodulatory peptide tuftsin, developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. It is approved in Russia as a nasal s…
BP and Cardiovascular Considerations The Phase 3 program documented modest, transient increases in systolic blood pressure (1.9-2.5 mmHg) and diastolic (1.7-1.8 mmHg) in the 4-6 hours after dosing. Heart rate increased …
PT-141 (bremelanotide) is a cyclic melanocortin receptor agonist that enhances sexual desire and arousal through a mechanism no other approved sexual health treatment uses: direct activation of MC4R receptors in the bra…
IV Infusion Self-Reported Adverse Events Note on labeling: the events below come from clinic-published infusion procedures and self-reported community sources. There is no Phase 2 or Phase 3 trial dataset for IV NAD+ ad…
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every living cell, essential for mitochondrial energy production, DNA repair, and sirtuin activation. NAD+ levels decline approximately 50% between ages …
Nicotinamide adenine dinucleotide (NAD+) is not a peptide — it's a coenzyme found in every living cell. But its role in aging biology is so central that it's become one of the most researched molecules in the longevity …
Why MOTS-c and Metformin Get Compared Both MOTS-c and metformin activate AMP-activated protein kinase (AMPK) — the cellular energy sensor that sits at the crossroads of metabolism, aging, and exercise adaptation. That s…
Adverse Events Most Commonly Self-Reported in Community Sources Note on labeling: The events below come from self-reported community sources (r/peptides, r/PeptideTherapy, peptide forums). They are not trial-grade incid…
Affiliate disclosure: vendor links in this article are affiliate links — The Peptide Catalog may earn a commission if you buy through them, at no additional cost to you. Where These Numbers Come From MOTS-c was first id…
Research findings on exercise performance: Systemic MOTS-c administration significantly enhanced physical performance in young (2-month), middle-aged (12-month), and old (22-month) mice, with the most pronounced effects…
Affiliate disclosure: vendor links in this article are affiliate links — The Peptide Catalog may earn a commission if you buy through them, at no additional cost to you. Ready to buy? See our MK-677 buying guide for for…